Mazor Robotics

Caesarea, Israel (original headquarters, now a base for Medtronic's surgical robotics growth)  All Israel companies → Founded 2001
Medical Device / Hardware Specialty-Focused AI
Neurosurgery Orthopedics
Radiology & Imaging AI Surgical AI
N/A (acquired by Medtronic in 2018) — N/A (acquired by Medtronic in 2018 for $1.7 billion)

Products

Mazor X System / Mazor X Stealth Edition
Mazor Robotics
Radiology & Imaging AI
The Mazor X System / Mazor X Stealth Edition is a robotic guidance platform for spine surgery, combining 3D planning, robotic guidance, and real-time navigation to enhance precision, predictability, and patient outcomes.

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About Mazor Robotics

Mazor Robotics, now a key component of Medtronic’s surgical robotics portfolio, developed advanced robotic guidance systems primarily for spine surgery. Its flagship technologies, such as the Mazor X™ Robotic Guidance System and the Renaissance® Surgical-Guidance System, transformed spinal procedures from freehand techniques to highly accurate, state-of-the-art guided interventions. These systems are designed to enhance precision and predictability in complex spinal and cranial procedures by integrating preoperative planning with intraoperative guidance and real-time 3D verification.

For physicians, the Mazor robotic guidance system, now part of Medtronic’s AiBLE™ surgical suite, offers robust preoperative planning software that allows for visualization and optimization of spinal elements with automatic anatomy recognition. During surgery, the system provides navigated visualization of instruments and interbodies, along with predictive software tools for holistic construct design. The integration with Medtronic’s StealthStation navigation technology, as seen in the Mazor X Stealth Edition and the newer Stealth AXiS system, further enhances capabilities by allowing surgeons to visualize anatomic motion, surgical adjustments, and patient alignment in real-time without repeated imaging. This comprehensive approach aims to improve surgical efficiency, reduce complications, and lead to better patient outcomes in both open, minimally invasive, and percutaneous spinal procedures.

Focus Areas

Robotic-assisted surgical guidance systems for spine and cranial procedures; preoperative planning software; intraoperative navigation and guidance; 3D imaging and verification; integration with surgical imaging and navigation platforms (e.g. Medtronic O-arm™ imaging system StealthStation™ navigation system).

Business Intelligence

Key InvestorsMedtronic, Johnson & Johnson Development Corp, Israel Healthcare Ventures, Oracle Investment Management, Inc., Phoenix Holdings Company, Alice Ventures, DOR Ventures, ProSeed Venture Capital Fund
PartnershipsMedtronic (strategic and equity investment agreement, exclusive worldwide distributor of Mazor X), Florida Hospital Nicholson Center (national training center)
AcquisitionsAcquired by Medtronic in December 2018 for approximately $1.64 billion
TechnologySmartAssist platform, 3D planning software, robotic guidance, real-time 3D verification, image processing, computerized anatomy recognition, integration with Medtronic StealthStation software
FDA Clearances15+ cleared products (estimated)

What Physicians Need to Know

Robotic-Assisted Surgical Guidance
Specializes in advanced robotic guidance systems, such as the Mazor Xu2122 Stealthu2122 Edition and Renaissance Guidance System, for highly precise spine and cranial procedures. These systems provide mechanical guidance to execute surgical plans with exceptional accuracy.
Preoperative 3D Planning
Offers robust preoperative planning software that enables surgeons to create individualized 3D surgical plans, visualize and optimize spinal elements, select implants, and determine optimal trajectories before entering the operating room.
Intraoperative Navigation & Guidance
Provides real-time intraoperative navigation and guidance, tracking the position of instruments in relation to the surgical anatomy and identifying this position on diagnostic or intraoperative images. The robotic arm assists in guiding instruments to the precise, pre-planned location.
3D Imaging & Verification
Features 3D imaging capabilities that convert 2D fluoroscopic projections into volumetric 3D images and utilize cross-modality image recording for comprehensive anatomical assessment and verification during surgery.
Minimally Invasive Focus
Designed to facilitate minimally invasive surgical techniques, leading to smaller incisions, reduced blood loss, less tissue damage, and potentially faster recovery times for patients.
Enhanced Accuracy & Predictability
Delivers exceptional sub-millimetric accuracy in implant placement, with reported precision rates between 98.7% and 100%, significantly enhancing surgical predictability and reducing complication rates.
Reduced Radiation Exposure
Minimizes the need for repeated intraoperative fluoroscopy, thereby reducing radiation exposure for both the patient and the surgical team.
Physician Tip

For physicians, Mazor Robotics systems stand out by offering unparalleled precision and predictability in spine and cranial procedures, enabling highly accurate execution of complex surgical plans. The advanced 3D preoperative planning software allows for truly individualized patient care, optimizing implant selection and trajectories. The integration of robotic guidance with real-time navigation enhances confidence and control during surgery, while facilitating minimally invasive approaches that benefit patient recovery through smaller incisions, less pain, and shorter hospital stays. Crucially, the surgeon maintains full control throughout the procedure, with the robot acting as a highly accurate and consistent assistant. The reduced radiation exposure for both patients and the surgical team is an additional significant advantage. These systems contribute to improved patient outcomes, including faster recovery and fewer complications, ultimately enhancing clinical reputation and patient satisfaction.

Mazor Robotics' systems are seamlessly integrated with leading surgical imaging and navigation platforms, notably the Medtronic O-armu2122 imaging system and the StealthStationu2122 navigation system. This integration provides a comprehensive and streamlined workflow, from preoperative planning to intraoperative execution and verification. The Mazoru2122 robotic guidance system is also part of Medtronic's broader AiBLEu2122 surgical suite, which aims to connect surgical technologies for personalized planning, execution, and post-operative analysis.

Products by Mazor Robotics

1 product in the directory

Mazor X System / Mazor X Stealth Edition
Mazor Robotics
Radiology & Imaging AI
The Mazor X System / Mazor X Stealth Edition is a robotic guidance platform for spine surgery, combining 3D planning, robotic guidance, and real-time navigation to enhance precision, predictability, and patient outcomes.

What the Web Says

Mazor Robotics, acquired by Medtronic in 2018, developed robotic guidance systems for spine surgery, including the SpineAssist, Renaissance, and Mazor X. These systems aim to improve accuracy, reduce complications, and facilitate minimally invasive procedures. While the technology has been praised for its precision and potential to enhance patient outcomes, some concerns regarding navigation accuracy and robot-related complications have been raised in medical literature.

Overall: Mixed

Strengths

  • Increased surgical accuracy and precision in screw placement.
  • Reduced complications and revision surgeries compared to freehand methods.
  • Enables minimally invasive approaches, leading to smaller incisions.
  • Decreased blood loss during surgery.
  • Shorter hospital stays and less post-operative pain for patients.
  • Facilitates complex spinal procedures like scoliosis correction.

Limitations

  • Potential for inaccurate navigation data, leading to misplaced instruments and nerve injury.
  • Robot-related complications, including nerve root injuries and durotomy, have been reported.
  • Hardware detachment issues with certain Mazor X systems, potentially causing the robot to fall during surgery.
  • Complication rates have not necessarily decreased with newer generation robots.
  • Some opinions suggest it's mainly a marketing gimmick, with patients wanting it more than surgeons seeing significant improvement.
  • A clinical consultant role with Mazor (now Medtronic) may involve a significant pay cut and less company benefits compared to other medical device sales roles.

Based on reviews from: Indeed.com, YouTube (Essentia Health), Reddit (r/stocks), OrthoIndy, Reddit (r/neurosurgery), Law Offices of Dr. Bruce G. Fagel & Associates, Fierce Biotech, PMC (PubMed Central), Reddit (r/neurosurgery), Joseph Spine Institute, Reddit (r/robotics), CTV News

Last updated: 2026-07-18

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Press & Coverage

Medical Device Network
Medtronic to buy Mazor Robotics under $1.64bn deal
Medtronic signed a definitive merger agreement to acquire Mazor Robotics for approximately $1.64 billion, strengthening its position in spine surgery technologies and robotic-assisted surgery systems. The deal was expected to close in Medtronic's third fiscal quarter ending January 25, 2019.
2018-09
PR Newswire
Medtronic To Acquire Mazor Robotics
Medtronic announced a definitive merger agreement to acquire all outstanding ordinary shares of Mazor Robotics for approximately $1.64 billion, aiming to accelerate the adoption of robotic-assisted surgery in spine. The acquisition was unanimously approved by both companies' boards of directors.
2018-09
MassDevice
Mazor Robotics acquired by Medtronic in $1.7B deal
Medtronic completed its $1.7 billion acquisition of Mazor Robotics, also announcing FDA 510(k) clearance for the co-developed Mazor X Stealth device. This acquisition aims to integrate Mazor's robotic systems with Medtronic's existing spine technologies for a comprehensive surgical solution.
2018-12
Medtronic
Medtronic Announces U.S. Commercial Launch of Mazor X Stealth(TM) Edition for Robotic-Assisted Spine Surgery
Medtronic announced the first U.S. patients treated with the Mazor X Stealthu2122 Edition for spine surgery following its commercial launch. This system offers an integrated solution for surgical planning, workflow, execution, and confirmation, combining robotics and navigation.
2019-01
Children's Hospital Colorado
Mazor X Robot Improves Pediatric Spine Surgery - Children's Hospital Colorado
Children's Hospital Colorado achieved 500 robot-assisted spine surgeries using the Mazor X robot, known as 'Mazie,' which has significantly impacted pediatric spinal surgery. The hospital is one of only four institutions in the U.S. using Mazor X in the pediatric space and conducting research on its efficacy.
2024-03
Neurospine
Navigation-Guided/Robot-Assisted Spinal Surgery: A Review Article - Neurospine
This review article discusses the evolution of robotic systems in spinal surgery, highlighting Mazor Robotics' SpineAssist as the first FDA-approved system in 2004, followed by Renaissance in 2011, and Mazor X in 2016. Studies indicate high accuracy rates for pedicle screw placement using Mazor X.
2024-03
PMC
Mazor X robot-assisted upper and lower cervical pedicle screw fixation: a case report and literature review - PMC
This case report and literature review details the first reported use of the Mazor X robot for atlantoaxial pedicle screw fixation, expanding its application in orthopedic surgery. The Mazor X system offers high accuracy and visualization for personalized screw placement, minimizing damage to critical structures.
2024-11
MedTech Dive
Medtronic nets FDA clearance for robotic spine system - MedTech Dive
Medtronic received FDA clearance for its Stealth AXiS surgical system, which builds upon the Mazor robotic platform to enhance its cranial and spinal technologies. This system integrates Mazor's robotics with Medtronic's StealthStation navigation technology.
2026-02

Frequently Asked Questions

The Medtronic Mazor X Stealth Edition is primarily used for robotic-assisted surgical guidance in spine and cranial procedures. It aids in precise positioning of surgical instruments and implants during both open and minimally invasive surgeries, including spinal fusion, deformity correction, and pedicle screw placement.
The Mazor X Stealth Edition seamlessly integrates Medtronic's StealthStation navigation system and O-armu2122 imaging system. This integration allows for comprehensive 3D preoperative planning, real-time intraoperative navigation, and verification, providing surgeons with enhanced visualization and guidance.
The Mazor X Stealth Edition has received FDA clearances, and as a Medtronic product, it adheres to stringent medical device regulations including good manufacturing practices and adverse event reporting. However, there have been documented adverse event reports in the MAUDE database, and a Class 2 recall was issued for the 'Snapshot' function due to potential navigation inaccuracies.
The capital cost for a Mazor X robot typically ranges from approximately $550,000 to $850,000. In addition to the initial purchase, there are estimated disposable supply costs of about $1,500 per case and potential annual maintenance fees.
Medtronic provides extensive support and training for the Mazor X Stealth Edition, including specialized 'Mazor Robotic Experience Labs' and educational resources through Medtronic Academy. These programs offer hands-on opportunities and aim to deepen understanding of the system's operation and integration with other Medtronic technologies.
Mazor Robotics was acquired by Medtronic in 2018, and its technology is now fully integrated into Medtronic's Neurosurgery business. This acquisition provides enhanced company stability, leverages Medtronic's global distribution channels, and fosters continued innovation in robotic-assisted surgical solutions for spine and cranial procedures.

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