Sigma-Aldrich (Merck KGaA)

Burlington, Massachusetts, United States (for MilliporeSigma in the US and Canada); Darmstadt, Germany (for Merck KGaA)  All United States companies → Founded 1975 (merger of Sigma Chemical Company and Aldrich Chemical Company)
Public (as part of Merck KGaA, which is publicly traded) — Acquired by Merck KGaA for $17 billion in 2015

Products

AIDDISON Explorer
Sigma-Aldrich (Merck KGaA)
Drug Discovery & Research
AIDDISSON Explorer is an AI-powered drug discovery platform combining generative AI with computer-aided drug design for molecular generation, virtual screening, ADMET prediction, and retrosynthesis planning.

See all 1 product →

About Sigma-Aldrich (Merck KGaA)

Sigma-Aldrich, operating as MilliporeSigma in the U.S. and Canada, is the life science business of Merck KGaA, Darmstadt, Germany. The company is a leading supplier to the global life science industry, offering a vast portfolio of over 300,000 products, technologies, and services. Their mission is to collaborate with the global scientific community to solve complex problems in life science, ultimately aiming to accelerate access to better health for people worldwide.

They empower scientists and engineers at every stage of discovery, from fundamental research to biotechnology development and pharmaceutical drug therapy production. Sigma-Aldrich focuses on providing state-of-the-art tools, services, and digital platforms to help research move faster and more effectively across various disciplines. Their expertise spans process solutions, advanced solutions, and discovery solutions, catering to a broad range of customers from biopharmaceutical facilities and government research sites to diagnostic labs and academic research groups.

Focus Areas

Life science research biotechnology development pharmaceutical drug therapy development and production lab materials specialty chemicals genomics cell culture analytical and chromatography capabilities drug discovery biomanufacturing biosafety testing AI-driven drug discovery process solutions advanced solutions discovery solutions

Business Intelligence

Key InvestorsMerck KGaA (parent company)
PartnershipsSiemens (strategic partnership for AI and data-driven drug discovery and development), Promega (co-development of novel technologies for drug discovery), Washington University in St. Louis, Innovative Biotech, GI Innovation, Biotheus, Synplogen, Beyond Benign, Korea Advanced Institute of Science and Technology (KAIST)
AcquisitionsAcquired by Merck KGaA in 2015; Sigma-Aldrich itself grew through various acquisitions including BioReliance (2012), Erbi Biosystems (2022), Mirus Bio (2024), Bio-Techne (2026, agreement to acquire)
TechnologyCloud-native deployment with ISO 27001-certified data security, AI-powered drug discovery platform (AIDDISON™ Explorer) combining generative AI, machine learning, and computer-aided drug design, integration with Siemens Xcelerator Platform and Dotmatics Scientific Intelligence Platform, SYNTHIA® API integration for synthesis-aware candidate design
FDA Clearancesunknown cleared products (estimated)

Products by Sigma-Aldrich (Merck KGaA)

1 product in the directory

AIDDISON Explorer
Sigma-Aldrich (Merck KGaA)
Drug Discovery & Research
AIDDISSON Explorer is an AI-powered drug discovery platform combining generative AI with computer-aided drug design for molecular generation, virtual screening, ADMET prediction, and retrosynthesis planning.

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Press & Coverage

Sigma-Aldrich (Press Release)
Merck KGaA, Darmstadt, Germany and Siemens Deepen Strategic Partnership to Accelerate AI and Data-Driven Drug Discovery and Development
Merck KGaA, Darmstadt, Germany and Siemens signed a Memorandum of Understanding to extend their strategic partnership, focusing on integrated software solutions, systems, and consumables that leverage automation, data, and AI to connect drug discovery, development, and manufacturing.
2025-09
Sigma-Aldrich
Fast-Tracking Drug Discovery with an AI Boost
This article highlights AIDDISONu2122, a new AI-powered drug discovery platform developed by Merck KGaA, Darmstadt, Germany, designed to accelerate the identification of promising molecules for new therapeutics. The platform aims to reduce the time and cost associated with early-stage drug development.
2024-03
Sigma-Aldrich (Press Release)
MilliporeSigma Launches First Ever AI Solution to Integrate Drug Discovery and Synthesis
MilliporeSigma introduced its first AI solution to integrate drug discovery and synthesis, combining generative AI, machine learning, and computer-aided drug design to enhance the success rate of new drugs and therapies. The platform virtually screens compounds and evaluates synthesis routes.
2023-12
Merck (Press Release)
Merck Expands Innovative Internal Generative AI Solutions Helping to Deliver Medicines to Patients Faster
Merck (known as MSD outside the US and Canada) has developed new internal generative AI-powered platforms to significantly reduce the time needed to produce clinical study documents, aiming to expedite the availability of life-saving medicines.
2025-06
PharmExec
Merck KGaA Acquires Sigma-Aldrich for $17 Billion
Merck KGaA announced its agreement to acquire Sigma-Aldrich for $17 billion, a move intended to expand Merck's EMD Millipore chemical and equipment division and increase its presence in North America and fast-growing Asian markets.
2014-09
ACS Publications - Chemical & Engineering News
Merck KGaA To Buy Sigma-Aldrich
Germany's Merck agreed to acquire Sigma-Aldrich for $17.0 billion, a deal that would combine two major suppliers of laboratory chemicals and drug manufacturing ingredients, creating a business with over 300,000 products and 2 million customers.
2010-11
Sigma-Aldrich (Press Release)
Merck Completes Sigma-Aldrich Acquisition
Merck announced the completion of its $17 billion acquisition of Sigma-Aldrich, establishing a leading player in the global life science industry with an enhanced product range and geographic reach.
2015-11
Sigma-Aldrich (Press Release)
MilliporeSigma Announces Opening of BioRelianceu00ae Testing Facility in Darmstadt, Germany to Support Drug Product Release in Europe
MilliporeSigma announced the opening of a new u20ac25M BioRelianceu00ae testing facility in Darmstadt, Germany, to support drug product release in Europe, strengthening its services for biopharma customers.
2026-07
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