Greycroft

VC New York, United States · Founded 2006

Greycroft partners with bold founders in AI, software, sustainability, and consumer brands to create lasting impact. They believe AI will dominate the software category over the next decade and seek to support founders reimagining industries across these sectors.

About Greycroft

Greycroft is a multi-stage venture firm with offices in New York and Los Angeles and a thesis spanning consumer, enterprise, and selective healthcare investing, with a strong brand built on early bets in companies like Venmo, Bumble, and Trade Desk. The firm operates separate seed and growth funds, with the seed fund focused on early-stage and the growth fund leading later rounds. For healthcare AI founders, Greycroft is a credible generalist with selective healthcare exposure rather than a healthcare specialist; the firm has done meaningful digital health and healthcare technology deals but does not lead with a healthcare-specific thesis. Plausible check sizes vary substantially by fund: 250K to 2M at seed, 5M to 25M at growth. The firm leads or co-leads at all stages. Founders building healthcare AI with strong B2B SaaS or consumer characteristics, category-defining ambition, and clear technical defensibility should approach. Founders pitching deep biotech, regulated medical devices, or research-stage clinical AI should look at life sciences specialists; Greycroft does not advertise that depth. Entry path is warm introduction through portfolio founders or operator networks in New York or Los Angeles, or LinkedIn outreach to partners (Dana Settle, Alan Patricof, others have public profiles). The firm reads inbound but the signal-to-noise is heavy. Diligence will be sharp on team, market structure, defensibility, and unit economics. Expect a generalist read with light healthcare market context. The value-add includes New York and LA network access, brand-driven syndicate signaling, and follow-on capacity from a multi-stage platform. Bring evidence of category leadership ambition and clear product-market traction.

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Healthcare AI tools backed by Greycroft

Tools made by companies in Greycroft's portfolio that we cover in the directory.

BrightHeart View Classifier
BrightHeart
Cardiology AI
BrightHeart's B-Right AI Platform, including the B-Right Views tool, provides AI-powered guidance and analysis for prenatal ultrasound exams, enhancing the detection of congenital heart defects and ensuring exam completeness.
OpenEvidence
OpenEvidence
Clinical Decision Support & Reference
OpenEvidence is an AI-powered clinical decision support platform providing physicians with immediate, referenced answers from peer-reviewed medical literature and offering tools for clinical documentation. It is free for verified U.S. healthcare professionals.
Fetal EchoScan
Brightheart
Cardiology AI
Brightheart's Fetal EchoScan is an FDA-cleared AI-powered ultrasound screening software that assists clinicians in the prenatal detection of congenital heart defects, ensuring comprehensive exams and optimizing workflow.
Hippocratic AI
Hippocratic AI
Patient Engagement & Education
Hippocratic AI offers safety-focused generative AI agents for healthcare, assisting with administrative, patient communication, and low-risk clinical tasks to enhance efficiency and address workforce shortages.
HOPPR
HOPPR
Developer Tools & APIs
HOPPR AI Foundry is a secure, purpose-built platform for accelerating the development, fine-tuning, and validation of medical imaging AI, built by radiologists for radiologists.
HealthVerity eXOs
HealthVerity
Drug Discovery & Research
HealthVerity eXOs is an agentic AI platform that accelerates real-world evidence (RWE) generation and epidemiological studies by translating plain-English questions into structured designs and analyses. It offers team-wide access to on-demand analytics across nationwide patient data.
Coding Intelligence (OpenEvidence Visits)
OpenEvidence
Clinical Decision Support & Reference
OpenEvidence is an AI copilot for doctors that helps them make high-stakes decisions at the point of care. It is the most widely used medical AI among verified U.S. clinicians, having supported over 200 million AI-powered clinical consultations.

Portfolio companies in our directory

Other portfolio companies

Companies in Greycroft's portfolio not currently in our directory.

  • Sequen AI · 2025
  • Penguin AI · 2024
  • Playhouse MD · 2025
  • Biologica
  • Boulder Care
  • Budgie Health
  • Calibrate Health

Team

Dana Settle
Co-Founder & Managing Partner
Ian Sigalow
Co-Founder & Managing Partner
John Elton
Partner
Brian Bustamante-Nicholson
Partner
Dylan Pearce
Partner
Katherine Power
Partner

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Last updated 2026-05-06. Sourced from this fund's published materials.
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