NAEOTOM Alpha.Pro

by Siemens Medical Solutions USA  · Based in United States →The accelerator for photon-counting CT performance at Dual Source speed.
Radiology

Regulatory Status Disclosed

Overview

NAEOTOM Alpha.Pro is an advanced dual-source photon-counting computed tomography (PCCT) scanner from Siemens Healthineers. It represents a significant evolution in medical imaging by directly registering each X-ray photon, enabling the acquisition of highly detailed anatomical images with functional information, reduced noise, and fewer artifacts compared to conventional CT.

This innovative system combines the precision of photon-counting technology with the speed of dual-source CT, offering ultra-high spatial resolution (down to 0.2 mm slice thickness) and spectral information in every scan at minimal radiation doses. It features fast scan speeds of up to 491 mm/sec and a temporal resolution of 66 ms, which is crucial for challenging patient groups. Embedded AI-powered productivity tools, such as myExam Companion and zero-click Recon&GO, streamline scanning workflows, optimize procedures, and automate image reconstruction to enhance efficiency and support rapid, confident diagnoses.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Photon-counting CT technology (QuantaMax detector)
  • Dual Source CT speed and temporal resolution (66 ms)
  • Ultra-high spatial resolution (0.2 mm slice thickness)
  • Low radiation dose capabilities
  • Spectral information in every scan (Quantum Spectral Imaging)
  • AI-powered scanning workflows (myExam Companion)
  • Automated image reconstruction (zero-click Recon&GO)
  • Fast scan speeds (up to 491 mm/sec)
  • Improved contrast-to-noise ratio
  • Quantum HD technology for detailed anatomy visualization

Use Cases

  • Cardiovascular imaging (e.g., highly calcified coronary arteries, heart valves, without beta-blockers)
  • Oncology (e.g., tumor development, metastases, perfusion and iodine maps)
  • Pediatrics (e.g., scanning without sedation, low-dose imaging)
  • Pulmonology (e.g., free-breathing scanning, reduced breath-hold)
  • Neurology (e.g., stroke assessments, small cerebral blood vessels)
  • Trauma and emergency care (e.g., time-critical treatments)

What Physicians Need to Know

DICOM Support & Standards
NAEOTOM Alpha.Pro produces CT images in DICOM format, ensuring compatibility with standard medical imaging systems.
PACS Integration Method
Seamless integration with PACS solutions, such as Sectra's, allows radiologists to view and post-process photon-counting CT (PCCT) exams from any workstation without needing to switch applications.
Reading Room Workflow Impact
Embedded AI-powered productivity tools, including myExam Companion and zero-click Recon&GO, accelerate scanning workflows, automate image reconstruction, and reduce manual tasks, optimizing reading workflows and leading to more efficient patient pathways.
AI Model Architecture (deep learning approach)
The system incorporates AI-powered productivity tools and AI-driven workflow enhancements. Siemens Healthineers has been training solution algorithms since 2021 using data from photon-counting CT scanners, strongly suggesting a deep learning approach.
Processing Speed (per study)
The NAEOTOM Alpha.Pro achieves scan speeds as fast as 491 mm/sec with a temporal resolution of 66 ms.
FDA Clearance Pathway (510k/De Novo)
The NAEOTOM Alpha class of photon-counting CT scanners, including the Alpha.Pro, received FDA clearance through the 510(k) premarket clearance pathway.
Supported Modalities (CT/MRI/X-ray/US)
The NAEOTOM Alpha.Pro is a dual-source Photon-Counting CT scanner.
Sensitivity & Specificity Data
The system provides ultra-high spatial resolution, improved image clarity with less noise and fewer artifacts, and reduced radiation exposure. It enables better diagnostic evaluation of coronary vessels, small abnormalities, and precise tumor characterization. One study indicated that PCCT conserved high diagnostic accuracy for interstitial lung disease with a 66% radiation dose reduction, and improved the ability to detect emphysema and lung nodule borders.
RSNA/ACR Validation
The NAEOTOM Alpha.Pro and its class were introduced and featured at RSNA 2024, indicating significant industry recognition and presentation of its capabilities.
Physician Tip

Leverage the NAEOTOM Alpha.Pro for challenging patient populations, such as those requiring low-dose imaging (pediatrics, oncology follow-ups), patients with heavy calcifications (cardiac), or those who cannot hold their breath (pulmonology), as it offers high-resolution imaging with reduced radiation and contrast media. Utilize the AI-powered workflow tools like myExam Companion and Recon&GO to streamline scanning and reading, potentially reducing scan times and manual post-processing, leading to faster diagnoses and improved patient throughput. The intrinsic spectral imaging capabilities can provide additional functional information in every scan, enhancing diagnostic confidence for complex cases.

The NAEOTOM Alpha.Pro offers seamless integration with existing PACS solutions, exemplified by its partnership with Sectra, allowing radiologists to access and post-process advanced photon-counting CT images directly within their diagnostic application. This eliminates the need for switching between multiple workstations or applications, thereby optimizing workflow efficiency and data management within the radiology department.

Details

Category Radiology & Imaging AI
Pricing Unknown
DeploymentOn-premise (medical device)
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

The NAEOTOM Alpha class CT systems, including NAEOTOM Alpha.Pro, received 510(k) clearance (K243523) from the U.S. Food and Drug Administration (FDA) on February 12, 2025, for use as a Computed Tomography X-ray System.

Integrations
EHR Not specified
Specialties Radiology

What the Web Says

The NAEOTOM Alpha.Pro from Siemens Healthineers is generally well-received, particularly for its photon-counting CT technology which is highlighted for improved image quality and lower radiation dose. Physicians appreciate the enhanced diagnostic capabilities, especially in complex cases like cardiac imaging and oncology. However, some reviews mention the high initial cost and the learning curve associated with new technology as potential drawbacks.

Overall: Positive

Strengths

  • Superior image quality due to photon-counting technology
  • Significantly reduced radiation dose for patients
  • Improved diagnostic accuracy, especially in complex anatomies
  • Enhanced visualization of fine details and small lesions
  • Potential for new clinical applications and research
  • Faster scan times in some protocols

Limitations

  • High initial capital investment and operational costs
  • Steep learning curve for technologists and radiologists
  • Requires significant infrastructure upgrades for some facilities
  • Limited long-term data on widespread clinical impact compared to conventional CT
  • Potential for workflow disruptions during initial implementation
  • Availability and service support may vary by region

Based on reviews from: Siemens Healthineers product pages and whitepapers, Radiology journals and medical technology publications, Healthcare IT news outlets, Physician forums and professional society discussions, Reddit (r/radiology, r/medicalphysics), Clinical review articles

Last updated: 2026-07-20

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Press & Coverage

Siemens Healthineers
Siemens Healthineers Announces First U.S. Installation of Naeotom Alpha.Pro Photon-Counting Computed Tomography Scanner
University Hospitals in Cleveland is the first U.S. healthcare institution to install the Naeotom Alpha.Pro, a dual-source photon-counting CT scanner that combines PCCT's precision with dual-source speed and AI-powered productivity. This scanner offers high-resolution imaging at low radiation doses, benefiting pulmonology, pediatric, and cardiology patients.
2025-09
Siemens Healthineers
Siemens Healthineers Receives FDA Clearance for Naeotom Alpha Class of Photon-Counting Computed Tomography Scanners
Siemens Healthineers received FDA clearance for its Naeotom Alpha class of photon-counting CT scanners, which includes the Naeotom Alpha.Pro, a second dual-source CT scanner, and the Naeotom Alpha.Prime, the world's first single-source PCCT. This clearance broadens the availability of this technology, enabling more detailed anatomical images with lower radiation doses.
2025-03
AuntMinnie.com
FDA clears Siemens' Naeotom Alpha class of PCCT scanners - AuntMinnie
The FDA has cleared Siemens Healthineers' Naeotom Alpha class of photon-counting CT scanners, including the Naeotom Alpha.Pro, a dual-source CT scanner, and the Naeotom Alpha.Prime, a single-source PCCT. The Naeotom Alpha.Pro combines photon-counting technology with dual-source speed, allowing for fast scan speeds and high temporal resolution.
2025-03
Applied Radiology
Siemens Healthineers Debuts New Photon-Counting CT Systems at RSNA
Siemens Healthineers unveiled the Naeotom Alpha.Pro and Naeotom Alpha.Prime photon-counting CT scanners at the RSNA conference, combining rapid scan times with high-resolution precision. The dual-source Naeotom Alpha.Pro offers scan times up to 491 mm/sec, enabling sedation-free scanning for children and less breath-holding for pulmonology patients.
2024-12
Siemens Healthineers
Siemens Healthineers Expands Photon-Counting CT Portfolio
Siemens Healthineers introduced the Naeotom Alpha class, expanding its photon-counting CT portfolio with the dual-source Naeotom Alpha.Pro and the world's first single-source Naeotom Alpha.Prime. This expansion aims to make powerful photon-counting technology accessible to more clinicians and patients, offering high image quality at low radiation doses.
2024-12
Applied Radiology
University Hospitals Becomes First in U.S. to Install Siemens Naeotom Alpha.Pro Photon-Counting CT | Applied Radiology
University Hospitals in Cleveland is the first U.S. health system to install the Naeotom Alpha.Pro, Siemens Healthineers' dual-source photon-counting CT scanner. This installation signifies a major step in expanding access to advanced imaging, offering highly detailed anatomical visualization with reduced noise, fewer artifacts, and lower radiation exposure.
2025-09
European Cardiology
The New Era of Computed Tomography: Photon-Counting, Precision and Patient Safety
University Hospitals Health System in Cleveland became one of the first American institutions to install Siemens Healthineers' Naeotom Alpha.Pro, a dual-source photon-counting CT system, in 2025. This article discusses the technological leap from energy-integrating to photon-counting CT, highlighting enhanced contrast resolution, reduced electronic noise, and improved tissue differentiation.
2025-11
American Hospital of Paris
The American Hospital of Paris acquires groundbreaking photon-counting CT scanner
The American Hospital of Paris became the first private French hospital to acquire a NAEOTOM Alpha.Pro photon-counting CT scanner from Siemens Healthineers. This acquisition is part of the hospital's innovation strategy, aiming to benefit approximately 12,000 patients annually in cardiology, oncology, and pediatrics with high-resolution images and minimal radiation exposure.
2025-11

Videos

Product demos, reviews, and walkthroughs for NAEOTOM Alpha.Pro.

View all on YouTube

Frequently Asked Questions

The NAEOTOM Alpha.Pro integrates AI-powered productivity tools like myExam Companion and Recon&GO to accelerate scanning and reading workflows. These tools automate tasks such as patient positioning, image reconstruction, and post-processing, aiming to reduce manual steps and inter-operator variability. This can lead to faster diagnoses and optimized clinical decision-making by providing conclusive, high-resolution images.
The NAEOTOM Alpha class, which includes the Alpha.Pro, has received FDA clearance for clinical use. As a major medical device manufacturer, Siemens Healthineers adheres to stringent regulatory standards like HIPAA and GDPR, implying robust measures for patient data security and privacy within its systems.
While the NAEOTOM Alpha.Pro's AI aims to enhance efficiency and image quality, like all AI, it operates based on trained data and may have inherent limitations or potential biases depending on the dataset used for its development. Physician oversight remains crucial for interpreting results, especially in complex or atypical cases, ensuring clinical context and ultimate diagnostic responsibility.
The NAEOTOM Alpha.Pro, with its photon-counting technology and AI, offers ultra-high spatial resolution at lower radiation doses and provides spectral information in every scan, surpassing conventional CT in detail and contrast-to-noise ratio. It is designed to streamline workflows and integrate with existing PACS/RIS, though proper IT infrastructure configuration is essential for smooth data flow and to unlock its full potential.
Specific pricing for the NAEOTOM Alpha.Pro is not publicly disclosed, as it is a high-end medical capital equipment. Pricing typically involves a significant upfront investment for the system itself, with additional costs for service contracts, software updates, and potentially subscription-based access to certain advanced AI applications or features. Interested institutions should contact Siemens Healthineers directly for detailed quotations.
Siemens Healthineers typically provides comprehensive training programs for medical professionals and staff on the operation and utilization of their advanced imaging systems, including the AI-powered features of the NAEOTOM Alpha.Pro. This often includes on-site training, educational resources, and ongoing technical support to ensure optimal performance and user proficiency.

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Suggest an Edit → | Last Verified: 2026-04-19 | First Added: 2026-04-19
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