NAEOTOM Alpha

by Siemens Medical Solutions USA  · Based in United States →CT redefined. The world's first photon-counting CT.
Cardiology Oncology Radiology

Contact for pricing
Regulatory Status Disclosed

Overview

NAEOTOM Alpha, developed by Siemens Healthineers, represents a paradigm shift in computed tomography (CT) imaging as the world’s first commercially available photon-counting CT scanner. Unlike conventional CT systems that measure the total energy of X-rays, NAEOTOM Alpha’s revolutionary QuantaMax detector directly converts individual X-ray photons into digital electrical signals. This direct conversion eliminates electronic noise and preserves vital energy information, leading to unprecedented image sharpness, contrast, and high spatial resolution down to 0.2 mm slice thickness.

The system offers significant clinical advantages, including the potential for substantially lower radiation doses and reduced contrast agent use, enhancing patient safety and expanding the reach of CT imaging to previously excluded patient populations. Key features such as Quantum Spectral Imaging provide spectral information with every scan, regardless of speed or resolution, enabling precise functional evaluation. Its Dual Source technology delivers exceptional temporal resolution (66 ms) and rapid scan speeds (up to 74 cm/sec), crucial for challenging imaging tasks like cardiac CT without the need for beta-blockers. Furthermore, AI-powered solutions like myExam Companion streamline workflows, optimize scanning procedures, and assist radiologists in reading cases, ensuring consistent precision and meaningful answers for confident clinical decision-making.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Photon-Counting Detector (QuantaMax detector)
  • Ultra-High Spatial Resolution (down to 0.2 mm slice thickness)
  • Significantly Lower Radiation Dose
  • Spectral Information in Every Scan (Quantum Spectral Imaging)
  • Dual Source Technology (66 ms temporal resolution, up to 74 cm/sec scan speed)
  • Improved Contrast-to-Noise Ratio with Eliminated Electronic Noise
  • AI-powered myExam Companion for workflow optimization
  • Ability to scan previously excluded patients (e.g., high heart rate, high BMI)
  • Quantum Iterative Reconstruction
  • Full Vectron X-ray power

Use Cases

  • Redefine cardiovascular CT (fine vessel visualization, stent assessment)
  • Redefine oncology CT (observing tumor development and metastases)
  • Redefine neurology CT (assessing small anatomical details in cerebral blood vessels)
  • Redefine pulmonology CT (lung follow-up checks, free-breathing scans)
  • Emergency medicine (rapid and precise imaging for trauma patients)
  • Radiation therapy planning preparation

What Physicians Need to Know

DICOM Support & Standards
NAEOTOM Alpha provides standard DICOM support, with conformance statements available for various syngo CT software versions.
PACS Integration Method
Seamless integration with PACS, such as Sectra, allows radiologists to access NAEOTOM Alpha's photon-counting CT images and spectral post-processing tools directly within their existing workflow, eliminating the need to switch workstations.
Reading Room Workflow Impact
AI-enabled solutions, including myExam Companion and advanced visualization tools, are integrated to accelerate scanning workflows, automate post-processing (e.g., CPRs, calcium scoring, vessel visualization), and enhance reading productivity. This can lead to significant time savings (e.g., 74% for abdomen, 82% for brain acquisitions) and consistent results.
AI Model Architecture (deep learning approach)
The NAEOTOM Alpha class utilizes artificial intelligence and automation, with solution algorithms trained since 2021 using data from photon-counting CT scanners. It incorporates deep learning and transfer learning to enhance image utility and streamline processes like image reconstruction (Recon&GO).
Processing Speed (per study)
The NAEOTOM Alpha.Peak model offers a fast scan speed of up to 737 mm/sec with a temporal resolution of 66 ms and a gantry rotation time of 0.25 seconds. Other models like Alpha.Pro achieve 491 mm/sec and Alpha.Prime 345 mm/sec, both with 66 ms temporal resolution.
FDA Clearance Pathway
NAEOTOM Alpha received initial FDA clearance in September 2021 through the 510(k) premarket clearance pathway, demonstrating substantial equivalence to a predicate device. The NAEOTOM Alpha class received FDA clearance in March 2025.
Supported Modalities
NAEOTOM Alpha is a Computed Tomography (CT) scanner, specifically leveraging photon-counting CT technology.
Sensitivity & Specificity Data
The technology offers the potential for the highest diagnostic sensitivity and specificity, enabling the detection and characterization of even the smallest structures. It provides high-resolution images at minimal dose, spectral information in every scan, and improved contrast at lower noise. Radiation dose can be reduced by as much as 50% while maintaining or improving image quality.
RSNA/ACR Validation
NAEOTOM Alpha has been a prominent highlight at major radiology conferences, including RSNA 2021, 2022, and 2024, where Siemens Healthineers showcased the scanner and presented clinical and research findings.
Physician Tip

Leverage NAEOTOM Alpha's ultra-high resolution and intrinsic spectral imaging for confident diagnosis of small structures and subtle abnormalities in challenging cases across cardiology, oncology, neurology, and pulmonology. Utilize the integrated AI-powered workflow tools like myExam Companion and Recon&GO to significantly reduce scan setup and post-processing time, minimizing inter-operator variability and enhancing efficiency. Capitalize on the reduced radiation dose and rapid scan speeds, which can decrease or eliminate the need for sedation in sensitive patient populations, such as pediatrics, and allow for more frequent follow-up scans. Employ the spectral data for precise functional evaluation, quantitative measurements, and advanced visualizations like virtual calcification removal in CTA, leading to clearer diagnostic insights.

NAEOTOM Alpha supports standard DICOM protocols for image exchange. Its AI-powered solutions are deeply integrated into the scanner's operational workflow and advanced visualization tools, enhancing the overall CT process. Furthermore, partnerships with PACS vendors like Sectra enable seamless integration of photon-counting CT images and spectral post-processing capabilities directly into existing reading room workflows, avoiding the need for separate applications or workstations.

Details

Category Radiology & Imaging AI
Pricing Contact for pricing
  • Pricing for high-end CT systems like NAEOTOM Alpha can range from $1 million to over $2 million, but direct sale pricing requires consultation
DeploymentOn-premise
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

The NAEOTOM Alpha, the world's first photon-counting computed tomography (CT) scanner, received FDA 510(k) clearance on September 30, 2021 (K243523 for the NAEOTOM Alpha class, which includes the original NAEOTOM Alpha).

Integrations
EHR Not specified
Specialties Cardiology, Oncology, Radiology

What the Web Says

The NAEOTOM Alpha, Siemens Healthineers' photon-counting CT scanner, is widely praised for its significant advancements in medical imaging. Reviewers highlight its ability to deliver higher resolution images with lower radiation doses, improving diagnostic accuracy, especially for complex cases like cardiac imaging and oncology. While the technology is revolutionary, its high cost and the learning curve for new workflows are noted as potential considerations.

Overall: Positive

Strengths

  • Significantly improved image resolution and clarity due to photon-counting technology.
  • Reduced radiation dose for patients, enhancing safety.
  • Enhanced contrast-to-noise ratio, improving visualization of subtle details.
  • Better differentiation of materials and tissue types.
  • Potential for earlier and more accurate disease detection.
  • Improved diagnostic capabilities for complex conditions like cardiac and oncology cases.

Limitations

  • High initial investment cost for the equipment.
  • Requires new workflows and training for medical staff.
  • Potential for longer scan times in some specific applications compared to conventional CT.
  • Data storage and processing requirements may be higher.
  • Limited availability in healthcare facilities due to its newness and cost.
  • Specific applications and benefits are still being explored and validated.

Based on reviews from: Siemens Healthineers official product page, Radiology Today, AuntMinnie.com, European Society of Radiology (ESR) publications, Journal of the American College of Cardiology (JACC) publications, Various medical technology review sites and forums

Last updated: 2026-07-19

Ratings & Reviews

No reviews yet. Be the first to review this tool!

Rate NAEOTOM Alpha

Clinical Value
Ease of Use
Integration
Support & Docs
Value for Money

Press & Coverage

AuntMinnie
FDA clears Siemens' Naeotom Alpha class of PCCT scanners
The U.S. FDA has cleared Siemens Healthineers' Naeotom Alpha class of photon-counting CT (PCCT) scanners, which includes the original Naeotom Alpha (now Naeotom Alpha.Peak), Naeotom Alpha.Pro, and Naeotom Alpha.Prime. This expands the availability of photon-counting CT technology for clinical use.
2025-03
Siemens Healthineers
Siemens Healthineers Receives FDA Clearance for Naeotom Alpha Class of Photon-Counting Computed Tomography Scanners
Siemens Healthineers announced FDA clearance for its Naeotom Alpha class of PCCT scanners, including dual-source and single-source models. This clearance aims to broaden the availability of this advanced imaging technology, which offers detailed anatomical images with lower radiation doses.
2025-03
RT - Respiratory Therapy
FDA Clears Siemens Naeotom Alpha CT Scanning Device | RT - Respiratory Therapy
The FDA cleared the Siemens Naeotom Alpha, the world's first photon-counting CT scanner, in October 2021. This device represents a significant technological advancement in CT imaging, providing more detailed information with less image noise by counting individual X-ray photons.
2021-10
Siemens Healthineers
Siemens Healthineers Announces First U.S. Installation of Naeotom Alpha.Pro Photon-Counting Computed Tomography Scanner
University Hospitals health system in Cleveland became the first U.S. institution to install the Naeotom Alpha.Pro, a dual-source photon-counting CT scanner. This installation expands access to advanced imaging, offering high-resolution images at low radiation doses and benefiting various patient populations.
2025-09
Imaging Technology News
FDA Grants 510(k) Clearance for New Class of Photon-Counting CT Scanners
The FDA granted 510(k) clearance for the Naeotom Alpha class of PCCT scanners, including the Naeotom Alpha.Prime, the first single-source PCCT scanner. These scanners offer reduced scan times and enhanced detection of small abnormalities.
2025-03
RAD Magazine
Photon-counting CT family gains two new members - RAD Magazine - The voice of medical imaging and clinical oncology
Siemens Healthineers introduced the Naeotom Alpha class, adding the Naeotom Alpha.Pro (a second dual-source scanner) and the Naeotom Alpha.Prime (the world's first single-source photon-counting CT scanner). This expansion aims to make photon-counting technology more accessible.
2025-02
Journal of Advanced Health Care
The revolution of photon-counting CT towards new horizons of diagnostic imaging - Journal of Advanced Health Care
This peer-reviewed article discusses how NAEOTOM Alpha with Quantum Technology is revolutionizing CT by providing high-resolution images at low doses with inherent spectral information. It highlights the potential for improved diagnostic evaluation in various clinical applications.
2024-04
PMC (PubMed Central)
Photon-counting detector CT: early clinical experience review - PMC
This review article details the early clinical experience with photon-counting detector CT, including the NAEOTOM Alpha. It highlights improved iodine contrast, lesion conspicuity, and enhanced visualization of coronary arteries and bone details.
2023-07

Videos

Product demos, reviews, and walkthroughs for NAEOTOM Alpha.

View all on YouTube

Frequently Asked Questions

NAEOTOM Alpha integrates AI for automated patient positioning, accelerated scanning workflows via myExam Companion, and streamlined image reconstruction with Recon&GO. These AI tools enhance diagnostic precision by providing advanced visualization and decision support, ultimately optimizing the CT workflow from acquisition to reading.
The original NAEOTOM Alpha received FDA clearance in October 2021, and its expanded class (including Pro and Prime models) was cleared in March 2025. This regulatory approval confirms the system's safety and effectiveness for clinical use, including its integrated AI-powered features.
As an FDA-cleared medical device, NAEOTOM Alpha adheres to stringent healthcare data privacy regulations and security protocols. Its AI processing typically occurs within a secure, often on-premise, environment or through compliant cloud solutions, ensuring patient data remains protected.
The primary alternatives are conventional energy-integrating detector CT scanners. NAEOTOM Alpha, as a photon-counting CT, differentiates itself with superior image resolution, lower radiation dose, intrinsic spectral information, and advanced AI for workflow automation and enhanced diagnostic detail, which conventional CTs cannot provide.
The initial hardware cost for a NAEOTOM Alpha system is approximately US$5 million, significantly higher than conventional CT scanners, plus recurring service and software fees. This investment is justified by its ability to provide unprecedented image detail at lower doses, expand patient reach, and streamline workflows with AI, potentially leading to more confident diagnoses and improved patient outcomes.
While NAEOTOM Alpha offers significant advancements, potential considerations include its high initial cost and the need for specialized training for clinicians to fully interpret the novel photon-counting data. Additionally, the increased image quality might lead to more incidental findings, requiring careful clinical evaluation.
Siemens Healthineers states that its AI applications are trained on extensive datasets from years of photon-counting clinical experience, aiming for accurate and tailored diagnostic tools. As an FDA-cleared device, its AI algorithms undergo rigorous validation to ensure performance and minimize bias across diverse patient demographics.

Related Tools

OCTA
OCTA
Clinical Decision Support & Reference
OCTA Flow is an AI-powered platform that assists ophthalmologists in analyzing Optical Coherence Tomography Angiography (OCTA) scans to enhance diagnostic accuracy and efficiency.
Smart Reporting
Smart Reporting
Clinical Decision Support & Reference
A German health tech startup uses artificial intelligence to cut time spent on medical reports and improve patient care. Founded by a radiologist, Smart Reporting aims to standardize reporting and minimize documentation time, addressing the looming threat of physician shortage in Europe.
RetiVue EntireEye Imaging
RetiVue, LLC
Ophthalmology AI
RetiVue manufactures ultrawidefield retinal cameras with automatic image capture, aiming to aid in the early documentation of eye disease and prevent blindness. Their EntireEye Imaging System offers both desktop and portable options, providing true color, high-detail images with a wide field of view for patients from infancy to adulthood.
LesionQuant
CorTechs Labs
Neurology AI
LesionQuant, an FDA-approved AI product by CorTechs Labs, is particularly useful for patients with multiple sclerosis. It provides brain structure data and quantifies the number, size, and location of lesions, comparing them to prior studies.
Augmentiqs Augmented Reality Microscope (ARM)
Augmentiqs Medical Ltd.
Clinical Decision Support & Reference
Augmentiqs integrates augmented reality into existing microscopes, providing real-time access to digital pathology software, AI algorithms, and telepathology capabilities directly within the microscope's field of view.
AI Optics Sentinel Camera
AI Optics
Ophthalmology AI
AI Optics' Sentinel Camera is an FDA 510(k)-cleared handheld retinal imaging system designed to capture high-quality images for retinal disease screening, with future plans for integrated AI-based screening software for diabetic retinopathy, glaucoma, and macular degeneration.

See all Radiology & Imaging AI tools →

More from Siemens Medical Solutions USA

ACUSON Sequoia Diagnostic Ultrasound System
Siemens Medical Solutions USA
Radiology & Imaging AI
The ACUSON Sequoia Diagnostic Ultrasound System by Siemens Healthineers is a premium platform featuring BioAcoustic imaging, InFocus technology, and AI-powered tools to deliver consistent, high-resolution ultrasound imaging across diverse patient types and clinical applications.
AI Rad Companion (Engine)
Siemens Medical Solutions USA
Radiology & Imaging AI
Siemens AI-Rad Companion (Engine) is an FDA-cleared, AI-powered, cloud-based platform that streamlines radiology workflows and enhances diagnostic precision through automated image post-processing and structured reporting across multiple modalities.
AI-Rad Companion (Musculoskeletal)
Siemens Medical Solutions USA
Radiology & Imaging AI
AI-Rad Companion (Musculoskeletal) by Siemens Medical Solutions USA is an FDA-cleared AI-powered image processing software for quantitative and qualitative analysis of musculoskeletal conditions from CT DICOM images, supporting radiologists and physicians in diagnostic evaluation.
AI-Rad Companion Engine
Siemens Medical Solutions USA
Radiology & Imaging AI
The AI-Rad Companion Engine is an AI-powered, cloud-based platform by Siemens Medical Solutions USA that automates post-processing and enhances diagnostic precision in medical image interpretation across multiple modalities.

View company profile →

Suggest an Edit → | Last Verified: 2026-04-19 | First Added: 2026-04-19
AI Tool Finder
AI-powered search. Results may not be comprehensive.