NeuroQuant

by CorTechs Labs  · Based in United States →Empowering precision in neurological and oncological diagnostics with AI-driven quantitative imaging.
Neurology Oncology Radiology

Subscription
Regulatory Status Disclosed

Overview

NeuroQuant by CorTechs Labs (also known as Cortechs.ai) is a fully automated advanced imaging software designed for comprehensive brain MRI segmentation and volumetric quantification. This AI-powered medical device aids physicians in the detection, diagnosis, and monitoring of a wide range of neurological conditions by providing objective, quantitative data on brain structure volumes and lesion analysis.

The software integrates seamlessly into radiology workflows, offering fast and accurate analysis of 3D T1 MRI scans, and optionally T2 FLAIR and T2* GRE/SWI series for lesion quantification. NeuroQuant compares individual patient brain structure volumes to a unique normative database, which includes data from healthy individuals aged 3 to 100, normalized for age, gender, and intracranial volume.

Key functionalities include longitudinal tracking to assess changes in brain structure volumes and lesions over time, customizable volumetric reports, and advanced capabilities for segmenting and quantifying Amyloid-Related Imaging Abnormalities (ARIA) in Alzheimer’s patients, as well as various brain tumors.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Fully automated brain segmentation and volumetric analysis
  • Quantitative 3D T1 MRI post-processing image analysis
  • Comparison to normative database (ages 3-100, age/gender matched)
  • Longitudinal tracking of brain structure volumes and lesion changes over time
  • Detection and quantification of ARIA-E and ARIA-H
  • Segmentation and quantification of brain lesions (T2 FLAIR hyperintense, T2* GRE/SWI hypointense)
  • Customizable volumetric reports
  • Seamless integration into PACS systems
  • Cloud-based AI software
  • Supports data from all major MRI manufacturers

Use Cases

  • Assessment of neurodegenerative diseases (e.g., Alzheimer's, other dementias)
  • Monitoring Multiple Sclerosis (MS) progression and treatment
  • Evaluation of Traumatic Brain Injury (TBI)
  • Diagnosis and assessment of epilepsy
  • Quantification of brain tumors (gliomas, metastases, meningiomas)
  • Assessment of brain development abnormalities

What Physicians Need to Know

Brain MRI/CT Analysis
NeuroQuant is an FDA-cleared software that provides automated segmentation and precise volumetric analysis of brain structures from 3D MRI images, comparing them to age- and sex-matched normative databases. It measures volumes of various structures, including the hippocampus, amygdala, ventricles, cortical gray matter, and white matter. NeuroQuant CT specifically enhances conspicuity and provides automated analysis for diagnostic decision-making on CT scans, including stroke detection. Specialized modules like NeuroQuant MS visualize and track lesion volume changes, and NeuroQuant Brain Tumor offers automated segmentation and volumetric reporting for various brain tumors with longitudinal tracking.
Seizure Detection
NeuroQuant Seizure, through its Hippocampal Asymmetry Report, quantifies hippocampal volume and asymmetry, which is crucial for evaluating epilepsy, particularly temporal lobe epilepsy (TLE). This tool helps identify structural abnormalities linked to seizure activity, aids in diagnosis, and supports surgical planning and treatment monitoring by providing an Asymmetry Index against a normative database.
Neurodegenerative Disease Screening
NeuroQuant is a valuable tool for the early detection and monitoring of neurodegenerative conditions such as dementia, Alzheimer's disease, multiple sclerosis (MS), and traumatic brain injury (TBI) by identifying subtle changes in brain structures. It offers objective, volumetric data and color-coded analysis to support clinical impressions and includes specialized reports like the Age-Related Atrophy (Dementia Report), Multi-Structure Atrophy (MSA Report), and Microvascular Report for white matter hyperintensities and automated Fazekas scoring. The software also enables longitudinal tracking of brain changes to monitor disease progression and treatment effectiveness.
Triage Prioritization Speed
NeuroQuant's Triage Brain Atrophy (TBA) report provides an efficient, in-depth review of regional and global brain structure volumes for assessing traumatic brain injury and other neurodegenerative conditions. The automated analysis of MRI data can be completed in minutes, offering quick insights into 33-47 brain structures and flagging abnormalities with color-coded results, thereby aiding in rapid assessment and potential prioritization.
Physician Tip

Utilize NeuroQuant for objective, quantitative data to complement visual MRI interpretation, especially for detecting subtle brain changes that might be missed otherwise. Leverage its longitudinal tracking capabilities to monitor disease progression and assess treatment efficacy in conditions like Alzheimer's, MS, and TBI. Employ the Hippocampal Asymmetry Report for precise evaluation in epilepsy, aiding in diagnosis and surgical planning. Consider NeuroQuant CT for automated analysis and conspicuity enhancement in stroke detection on CT scans. Use custom reports to tailor volumetric analysis to specific clinical questions or less common neurological conditions. Always interpret NeuroQuant results in conjunction with other clinical information for a comprehensive patient assessment.

NeuroQuant is designed for seamless integration into existing radiology workflows. It supports DICOM SR (Structured Reporting) output, facilitating interoperability with PACS, structured reporting systems (e.g., PowerScribe, Syngo.via), and EHR workflows, which helps reduce manual data entry and transcription errors. Strategic partnerships, such as with Siemens Healthineers, further enhance its integration into imaging ecosystems. The cloud-based platform ensures scalable deployment across healthcare networks, and its Brain Tumor module also integrates into radiation oncology and neurosurgical workflows.

Details

Category Neurology AI
Pricing Subscription Based on number of analyses; Based on number of installations
DeploymentCloud-based; Computing appliance (local)
Compliance
BAA Available Yes AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

NeuroQuant has received multiple FDA 510(k) clearances, with the latest NeuroQuant 5.0 cleared for advanced segmentation and quantification of MRI lesions, including Amyloid-Related Imaging Abnormalities (ARIA) in Alzheimer's patients, Traumatic Brain Injury (TBI), and Cerebral Amyloid Angiopathy (CAA). It is intended for automatic labeling, visualization, and volumetric quantification of segmentable brain structures and lesions from MR images.

Integrations
EHR Not specified
Specialties Neurology, Oncology, Radiology

What the Web Says

NeuroQuant is an FDA-cleared software that analyzes standard brain MRI images to provide precise volumetric measurements of brain structures. It helps physicians detect subtle changes in brain volume that may be associated with conditions like Alzheimer's disease, multiple sclerosis, and traumatic brain injury, often identifying atrophy more sensitively than visual inspection by radiologists. The software compares individual brain volumes to a normative database adjusted for age, sex, and cranial volume, offering objective data for diagnosis, treatment planning, and monitoring neurological conditions over time.

Overall: Positive

Strengths

  • More sensitive in detecting subtle brain atrophy and volume loss compared to traditional visual MRI interpretation.
  • Provides objective, quantitative data for brain structure volumes, reducing subjectivity in diagnosis.
  • Aids in earlier detection and monitoring of various neurological conditions, including Alzheimer's, MS, and TBI.
  • Integrates into existing radiology workflows and generates reports quickly.
  • Helps clinicians communicate findings more clearly with patients.
  • Validated against gold-standard research methods and supported by numerous peer-reviewed studies.

Limitations

  • Some neurologists not familiar with mold-related illnesses may be dismissive of NeuroQuant findings in that context.
  • Insurance coverage can vary, and some plans may require additional documentation or justification.
  • Requires specific MRI acquisition protocols for optimal accuracy, and artifacts can degrade results.
  • While good for quantifying volume loss, it is less effective at identifying non-volume-related abnormalities.
  • A low percentile finding is a flag, not a diagnosis, and needs to be interpreted alongside other clinical information.
  • Some users on Reddit have expressed frustration with doctors not taking NeuroQuant reports seriously or radiologists not fully interpreting the detailed findings.

Based on reviews from: Reddit, HealthAidb, YouTube, PMC, Radiology Today Magazine, South Jersey Radiology, Intermountain Medical Imaging, Cortechs.ai, InventUM

Last updated: 2026-07-18

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Press & Coverage

NeurologyLive
FDA Clears Cortechs.ai's NeuroQuant 5.0 Software for Quantification and Segmentation of ARIA-E and ARIA-H | NeurologyLive
The FDA has granted 510(k) clearance for Cortechs.ai's NeuroQuant 5.0 software, which offers advanced segmentation and quantification capabilities for MRI lesions associated with T2*-weighted gradient recalled echo and susceptibility weighted imaging, particularly for amyloid-related imaging abnormalities (ARIA) in Alzheimer's patients.
2024-09
Cortechs.ai
Cortechs.ai Expands NeuroQuantu00ae to Revolutionize Brain Tumor Imaging with AI
Cortechs.ai announced a major enhancement to its FDA-cleared NeuroQuantu00ae Brain Tumor software, introducing fully automated segmentation and volumetric reporting for brain metastases and meningiomas, expanding its capabilities beyond gliomas.
2025-07
Diagnostic Imaging
FDA Clears Updated AI Software for MRI Neuroimaging - Diagnostic Imaging
The FDA has granted 510(k) clearance for the updated NeuroQuantu00ae 5.0 software, which offers enhanced MRI-based AI capabilities for assessing patients being treated for Alzheimer's disease and other neurological conditions, with improved segmentation for amyloid-related imaging abnormalities (ARIA).
2024-09
BioSpace
Cortechs.ai Receives FDA 510(k) Clearance for Groundbreaking NeuroQuant 5.0 Software, Expanding Support for Quantification of ARIA-E and ARIA-H - BioSpace
Cortechs.ai announced FDA 510(k) clearance for its NeuroQuantu00ae 5.0 software, which introduces advanced segmentation and quantification capabilities for MRI lesions associated with T2*GRE and Susceptibility Weighted Imaging (SWI), particularly for Amyloid-Related Imaging Abnormalities (ARIA) in Alzheimer's patients.
2024-09
PR Newswire
Cortechs.ai and Siemens Healthineers Partner to Expand Global Access to NeuroQuantu00ae Technologies - PR Newswire
Cortechs.ai announced a strategic partnership with Siemens Healthineers to integrate and distribute its FDA-cleared NeuroQuantu00ae Lesion Surveillance through the Siemens Healthineers Digital Marketplace, aiming to accelerate global adoption of quantitative brain imaging.
2026-03
Cortechs.ai
Cortechs.ai Announces MFDS (KFDA) Approval of Global-Leading NeuroQuantu00ae V5 Platform in South Korea
Cortechs.ai received regulatory approval from South Korea's Ministry of Food and Drug Safety (MFDS) for the NeuroQuantu00ae V5 product platform, expanding its footprint in the South Korean healthcare market.
2026-02
Cortechs.ai
Advancing Brain Tumor Imaging with NeuroQuantu00ae Brain Tumor - Cortechs.ai
Cortechs.ai released NeuroQuant Brain Tumor v2.1, bringing substantial upgrades to glioma and meningioma segmentation models, informed by clinical feedback and expanded training data.
2026-05
PR Newswire
Cortechs.ai Announce Next-Gen NeuroQuantu00ae Brain Tumor: AI-Driven Metastasis & Meningioma Segmentation - PR Newswire
Cortechs.ai announced the immediate availability of its latest release of the FDA-cleared NeuroQuantu00ae Brain Tumor, now offering fully automated segmentation and volumetric reporting of brain metastases and meningiomas.
2025-07

Videos

Product demos, reviews, and walkthroughs for NeuroQuant.

View all on YouTube

Frequently Asked Questions

NeuroQuant is an FDA-cleared software that quantifies brain structure volumes from MRI scans, assisting in the diagnosis and monitoring of conditions like Alzheimer's disease, other dementias, Multiple Sclerosis, Traumatic Brain Injury, and epilepsy. It provides objective data to detect subtle changes in brain volume often missed by visual inspection alone, supporting early detection and tracking disease progression.
Yes, NeuroQuant has been FDA 510(k) cleared since 2006 for automatic labeling, visualization, and volumetric quantification of segmentable brain structures from MRI images. This clearance signifies it is deemed safe and effective for its intended clinical use as a medical device. Cortechs.ai also states full HIPAA compliance for its cloud-based systems, ensuring patient data security.
NeuroQuant is a commercially available, FDA-cleared tool often compared to research-oriented software like FreeSurfer, with NeuroQuant being better suited for routine clinical application due to its integrated normative database. While other commercial tools exist (e.g., Neuroreader, MSmetrix, Inbrain, volBrain), studies indicate that while inter-method reliability can be good, significant volume differences may occur between different software packages, necessitating careful consideration.
NeuroQuant typically operates on a subscription-based pricing model, which can be structured based on the number of analyses performed or the number of installations within a facility. Cortechs.ai offers flexible licensing options, including single, combo, or multi-report licenses, allowing practices to choose access to one or multiple types of NeuroQuant reports.
NeuroQuant should be used as a supplementary tool alongside clinical assessment and other diagnostic information, rather than a standalone diagnostic method. Occasional segmentation errors can occur, requiring visual inspection of the results for accuracy. Furthermore, its primary reliance on T1-weighted images may limit sensitivity compared to expert visual review utilizing both T1 and T2-weighted sequences for certain pathologies.
Cortechs.ai, the developer of NeuroQuant, asserts full compliance with HIPAA regulations for its cloud-based processing systems. Patient data is encrypted during transmission and storage, and systems are hosted in highly secure, audited facilities with HITRUST CSF certification. Account administrators can also configure data retention policies, including automatic deletion, to further enhance privacy.
While NeuroQuant reports are designed for clarity with numerical data and visual aids, there is an initial learning curve associated with their effective interpretation. Cortechs.ai provides training resources, including videos, to help physicians understand the comprehensive clinical assessments and ensure accurate utilization of the quantitative volumetric data in their practice.

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Suggest an Edit → | Last Verified: 2026-04-18 | First Added: 2026-04-18
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